Geneticists develop novel base editors

In a study published in Nature Biotechnology on Aug. 28, Gao Caixia’s group at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences and her collaborators at Qi Biodesign have reported a modular, CRISPR-free base editing system, which they call CyDENT, to achieve effective base editing in the nucleus, mitochondria and chloroplast genomes of plant and human cells.

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