First-ever ribosomal synthesis of cyclic peptides opens new avenues for next-generation drug design

Inside our cells, ribosomes—the tireless “protein factories” of life—have just shown off a new skill they haven’t used in billions of years. A research team has become the first in the world to successfully expand the range of ring-shaped backbones in proteins using ribosomes, which have traditionally only produced linear backbones.

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