The human genome is like a big ball of yarn, made up of 3 billion molecular units arranged in sequence and then wrapped up around itself. Within this ball of yarn are your genes, which are regions of DNA that get copied and then turned into miniature molecular machines called proteins. The three-dimensional structure of the yarn dictates which of your genes get turned into proteins, and when this system fails, disease develops. But until now, it has not been possible to visualize how different regions of DNA talk to each other across space and time.