In a study published in Nature on July 3, researchers from the Institute of Biophysics of the Chinese Academy of Sciences and the University of Toronto, Canada, discovered a novel anti-CRISPR protein called AcrIF25, which inhibits the activity of the CRISPR-Cas system by dismantling the I-F type CRISPR-Cas complex (Csy complex), providing a new approach for precise control of the CRISPR-Cas system.