Trying to untangle a knot in a mess of strings can be frustrating and time-consuming. But not so for molecular machines—molecules that convert chemical energy into mechanical work and motion. Machines from the AAA+ family, which exist in the cells of all living organisms from bacteria to humans, can, among their many functions, recognize misfolded protein chains and swiftly unravel them.
Revolving doors and efficient engines: How proteins escape a molecular tangle
