New insights into how bacteria control DNA synthesis open the door to next generation antimicrobials
Ribonucleotide reductases (RNR) are indispensable enzymes that convert ribonucleotides to deoxyribonucleotides (dNTPs), the precursors to make up DNA. Because DNA synthesis is fundamental to cell survival, RNR activity must be tightly controlled. In bacteria, this […]
